Movement disorders in 2014: Genetic advances spark a revolution in dystonia phenotyping.
January
31st
31st
Movement disorders in 2014: Genetic advances spark a revolution in dystonia phenotyping.
de Koning TJ, Tijssen MA - January 31, 2015
Nat Rev Neurol. 2015 Feb;11(2):78-9. doi: 10.1038/nrneurol.2014.254.
Genetic revelations in 2014 are testing traditional classification systems for movement disorders, and our approach to clinical diagnostics. Mutations in dystonia-associated genes lead to a spectrum of disorders with different phenotypes, underscoring the need for stringent clinical phenotyping of patients with movement disorders, as well as next-generation sequencing approaches.
Link to source: